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List of substances for condition Group: Atopic Disease

All Human Animal Risk/Association ReviewRows: 256

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Vitamin D3 📋✍⛔38585333Vitamin D level is inversely related to allergen sensitization for risking atopic dermatitis in early childhood
Probiotics 📋✍⛔38138183Probiotics and Prebiotics Orally Assumed as Disease Modifiers for Stable Mild Atopic Dermatitis: An Italian Real-Life, Multicenter, Retrospective, Observational Study
Ginsenosides 📋✍⛔38150707Ginsenoside F2-Mediated Intestinal Microbiota and Its Metabolite Propionic Acid Positively Impact the Gut-Skin Axis in Atopic Dermatitis Mice
Ginseng 📋✍⛔37569348Black Ginseng Extract Exerts Potentially Anti-Asthmatic Activity by Inhibiting the Protein Kinase Cθ-Mediated IL-4/STAT6 Signaling Pathway
Luteolin 📋✍⛔36946145Luteolin restored Treg/Th17 balance to ameliorate allergic rhinitis in a mouse model
Micronutrients 📋 ⛔38732239An Overview on Atopic Dermatitis, Oxidative Stress, and Psychological Stress: Possible Role of Nutraceuticals as an Additional Therapeutic Strategy
Resveratrol 📋✍⛔38001807Resveratrol and Its Derivatives in Inflammatory Skin Disorders-Atopic Dermatitis and Psoriasis: A Review
Apigenin 📋✍⛔37128812Transcriptomics reveals apigenin alleviates airway inflammation and epithelial cell apoptosis in allergic asthma via MAPK pathway
Fucoidan 📋✍⛔34801417Topical application of fucoidan derived from Cladosiphon okamuranus alleviates atopic dermatitis symptoms through immunomodulation
Glycyrrhizic Acid 📋✍⛔36099014Glycyrrhizic acid suppresses atopic dermatitis-like symptoms by regulating the immune balance
Melatonin 📋✍⛔38387700Melatonin restores DNFB-induced dysbiosis of skin microbiota in a mouse model of atopic dermatitis
Curcumin 📋✍⛔34634654Intranasal curcumin and sodium butyrate modulates airway inflammation and fibrosis via HDAC inhibition in allergic asthma
Licorice Root 📋✍⛔36267759Inhibitory effects of isoliquiritin on an atopic dermatitis model through the CD177/JAK2/STAT pathway in vitro and in vivo
Peony 📋 ⛔36057224Paeonia lactiflora Pallas extract alleviates antibiotics and DNCB-induced atopic dermatitis symptoms by suppressing inflammation and changing the gut microbiota composition in mice
Quercetin 📋✍⛔37496407The Alleviating Impacts of Quercetin on Inflammation and Oxidant-antioxidant Imbalance in Rats with Allergic Asthma
Vitamin E 📋✍⛔38186195Antioxidant defense of children and adolescents with atopic dermatitis: Association with disease severity
Wormwood 📋✍⛔37604330In vitro and in vivo anti-eczema effect of Artemisia annua aqueous extract and its component profiling
Astaxanthin 📋✍⛔33335525Improved Anti-Inflammatory Effects of Liposomal Astaxanthin on a Phthalic Anhydride-Induced Atopic Dermatitis Model
Blackcurrant 📋✍⛔30175796Orally Administered Polysaccharide Derived from Blackcurrants (Ribes nigrum L.) Improves Skin Hydration in Ultraviolet-Irradiated Hairless Mice
Cordyceps 📋✍⛔37030458Cordyceps militaris polysaccharide alleviates ovalbumin-induced allergic asthma through the Nrf2/HO-1 and NF-κB signaling pathways and regulates the gut microbiota
Docosahexaenoic Acid 📋✍⛔30892697The role of oral vitamins and supplements in the management of atopic dermatitis: a systematic review
Gardenia 📋 ⛔36980282Topical Administration of Gardenia jasminoides Extract Regulates Th2 Immunity in OVA-Induced Mice
Kaempferol 📋✍⛔37393173Kaempferol therapy improved MC903 induced-atopic dermatitis in a mouse by suppressing TSLP, oxidative stress, and type 2 inflammation
Lactobacillus plantarum 📋 ⛔38288067Probiotic Lactobacillus plantarum GUANKE effectively alleviates allergic rhinitis symptoms by modulating functions of various cytokines and chemokines
Medicinal Plants 📋 38603736Medicinal plants for allergic rhinitis: A systematic review and meta-analysis
Prebiotics 📋✍⛔38138183Probiotics and Prebiotics Orally Assumed as Disease Modifiers for Stable Mild Atopic Dermatitis: An Italian Real-Life, Multicenter, Retrospective, Observational Study
Sea Buckthorn 📋✍⛔35306042Total flavonoids of sea buckthorn (Hippophae rhamnoides L.) improve MC903-induced atopic dermatitis-like lesions
Astragalosides 📋✍⛔36411656Research progress of astragaloside IV in the treatment of atopic diseases
Baicalein 📋✍⛔33905439Extract of Scutellaria baicalensis induces semaphorin 3A production in human epidermal keratinocytes
Berberine 📋✍⛔33539814Berberine induces anti-atopic dermatitis effects through the downregulation of cutaneous EIF3F and MALT1 in NC/Nga mice with atopy-like dermatitis
Chlorogenic Acid 📋✍⛔35600782Optimization of the extraction process of high levels of chlorogenic acid and ginsenosides from short-term hydroponic-cultured ginseng and evaluation of the extract for the prevention of atopic dermatitis
Chrysin 📋✍⛔33919431Chrysin Inhibits TNFα-Induced TSLP Expression through Downregulation of EGR1 Expression in Keratinocytes
Cinnamon 📋✍⛔37187105Anti-inflammatory effect and metabolic mechanism of BS012, a mixture of Asarum sieboldii, Platycodon grandiflorum, and Cinnamomum cassia extracts, on atopic dermatitis in vivo and in vitro
Evening Primrose Oil 📋✍⛔30065580Effect of Evening Primrose Oil on Korean Patients With Mild Atopic Dermatitis: A Randomized, Double-Blinded, Placebo-Controlled Clinical Study
Mangiferin 📋 ⛔38621336Inhibition of macrophage MAPK/NF-κB pathway and Th2 axis by mangiferin ameliorates MC903-induced atopic dermatitis
Naringenin 📋✍⛔37837514Naringenin ameliorates atopic dermatitis by inhibiting inflammation and enhancing immunity through the JAK2/STAT3 pathway
Omega-3 Fatty Acids 📋✍⛔38442638Comparison of treatment efficacy of omega-3 fish oil and montelukast in ovalbumin-protease-induced allergic rhinitis model in rats
Skullcap 📋✍⛔38543055Anti-Atopic Effect of Scutellaria baicalensis and Raphanus sativus on Atopic Dermatitis-like Lesions in Mice by Experimental Verification and Compound-Target Prediction
Spirulina 📋✍⛔36789047Therapeutic efficacy of spirulina against ovalbumin and cigarette smoke-induced asthma-specific stress biomarkers in Sprague-Dawley rats
Vitamin B12 📋✍⛔35502578Efficacy and safety profile of antioxidants in the treatment of atopic dermatitis: A systematic review and meta-analysis of randomized controlled trials
Zinc 📋✍⛔36265320Zinc supplement reduces allergic responses through modulating the p38 MAPK pathway activation in an allergic rhinitis mouse model
Angelica 📋✍⛔38154523Sophora flavescens-Angelica sinensis in the treatment of eczema by inhibiting TLR4/MyD88/NF-κB pathway
Astragalus Root 📋✍⛔33370169Astragalus Polysaccharides Attenuate Ovalbumin-Induced Allergic Rhinitis in Rats by Inhibiting NLRP3 Inflammasome Activation and NOD2-Mediated NF- κ B Activation
Baicalin 📋✍⛔34929516Baicalin ameliorates 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin lesions in mice through modulating skin barrier function, gut microbiota and JAK/STAT pathway
Bee Propolis 📋✍⛔34834178Artepillin C Reduces Allergic Airway Inflammation by Induction of Monocytic Myeloid-Derived Suppressor Cells
Black Pepper 📋✍⛔32051090Piper Nigrum extract improves OVA-induced nasal epithelial barrier dysfunction via activating Nrf2/HO-1 signaling
Butyrate 📋 ⛔38159175Sodium Butyrate Ameliorates Atopic Dermatitis-Induced Inflammation by Inhibiting HDAC3-Mediated STAT1 and NF-κB Pathway
Calycosin 📋 38331120Calycosin enhances treg differentiation for alleviating skin inflammation in atopic dermatitis
Cannabidiol 📋✍⛔34056830Novel cannabidiol aspartame combination treatment (JW-100) significantly reduces ISGA score in atopic dermatitis: Results from a randomized double blinded placebo controlled interventional study
Chamomile 📋✍⛔34658853The Mechanism Action of German Chamomile ( Matricaria recutita L.) in the Treatment of Eczema: Based on Dose-Effect Weight Coefficient Network Pharmacology
CoQ10 📋✍⛔33743807The effect of Co-Q10 on allergic rhinitis and allergic asthma
EGCG 📋✍⛔35640712Epigallocatechin gallate relieves asthmatic symptoms in mice by suppressing HIF-1α/VEGFA-mediated M2 skewing of macrophages
Ellagic Acid 📋✍⛔33525403Anti-Inflammatory Effects of Ellagic Acid on Keratinocytes via MAPK and STAT Pathways
Fig 📋 ⛔36364740Efficacy and Safety of Fig ( Ficus carica L.) Leaf Tea in Adults with Mild Atopic Dermatitis: A Double-Blind, Randomized, Placebo-Controlled Preliminary Trial
Fish Oil 📋✍⛔38442638Comparison of treatment efficacy of omega-3 fish oil and montelukast in ovalbumin-protease-induced allergic rhinitis model in rats
Galangin 📋 38697189Ameliorative potential of galangin in murine model of ovalbumin-induced allergic rhinitis: a role of PI3K-PKB pathway
Gallic Acid 📋 ⛔34815684Gallic Acid Ameliorates Atopic Dermatitis-Like Skin Inflammation Through Immune Regulation in a Mouse Model
Ginger 📋✍⛔32312261Ginger Extract Versus Loratadine in the Treatment of Allergic Rhinitis: A Randomized Controlled Trial
Hyaluronic Acid 📋✍⛔35679095Cell-Type Specific Expression of Hyaluronan Synthases HAS2 and HAS3 Promotes Goblet Cell Hyperplasia in Allergic Airway Inflammation
Lycopene 📋✍⛔35642947An immune-shift induced by lycopene; from an eosinophil-dominant type towards an eosinophil/neutrophil-co-dominant type of airway inflammation
Magnolol 📋 38541664Magnolol Reduces Atopic Dermatitis-like Symptoms in BALB/c Mice
Mint 📋 ⛔37175425The Anti-Atopic Dermatitis Effects of Mentha arvensis Essential Oil Are Involved in the Inhibition of the NLRP3 Inflammasome in DNCB-Challenged Atopic Dermatitis BALB/c Mice
Nigella Sativa 📋✍⛔36243604Effects of nigella sativa oil on allergic rhinitis: an experimental animal study
Pine Bark 📋✍⛔29484729Pinus densiflora bark extract ameliorates 2,4-dinitrochlorobenzene-induced atopic dermatitis in NC/Nga mice by regulating Th1/Th2 balance and skin barrier function
Rosmarinic Acid 📋✍ 38417242Alleviation of allergic asthma by rosmarinic acid via gut-lung axis
Schisandra 📋✍⛔37512164The Anti-Inflammatory and Skin Barrier Function Recovery Effects of Schisandra chinensis in Mice with Atopic Dermatitis
Silymarin 📋✍⛔35614885Effect of herbal cream containing Fumaria officinalis and silymarin for treatment of eczema: A randomized double-blind controlled clinical trial
Sulforaphane 📋✍⛔36319916Sulforaphane prevents and reverses allergic airways disease in mice via anti-inflammatory, antioxidant, and epigenetic mechanisms
Aloe Vera 📋✍⛔33072415Comparing the Therapeutic Effects of Aloe vera and Olive Oil Combination Cream versus Topical Betamethasone for Atopic Dermatitis: A Randomized Double-blind Clinical Trial
Alpha-Linolenic Acid 📋✍⛔37178572Alpha-linolenic acid improves nasal mucosa epithelial barrier function in allergic rhinitis by arresting CD4+ T cell differentiation via IL-4Rα-JAK2-STAT3 pathway
Balloon Flower 📋✍⛔37187105Anti-inflammatory effect and metabolic mechanism of BS012, a mixture of Asarum sieboldii, Platycodon grandiflorum, and Cinnamomum cassia extracts, on atopic dermatitis in vivo and in vitro
Bergamot Essential Oil 📋✍⛔37267637Bergapten ameliorates combined allergic rhinitis and asthma syndrome after PM2.5 exposure by balancing Treg/Th17 expression and suppressing STAT3 and MAPK activation in a mouse model
Boswellic Acid 📋✍⛔36077254Evaluation of the Anti-Atopic Dermatitis Effects of α-Boswellic Acid on Tnf-α/Ifn-γ-Stimulated HaCat Cells and DNCB-Induced BALB/c Mice
Catalpol 📋 38041954Inhibitory effects of catalpol on DNCB-induced atopic dermatitis and IgE-mediated mast cells reaction
Cinnamaldehyde 📋 37275806Anti-Inflammatory Effect of Cinnamaldehyde in a Mouse Model of 2,4-Dinitrofluorobenzene-Induced Atopic Dermatitis
Coconut Oil 📋 ⛔28660089Does Inhalation of Virgin Coconut Oil Accelerate Reversal of Airway Remodelling in an Allergic Model of Asthma?
Conjugated Linoleic Acid 📋✍⛔33206422Topical Application with Conjugated Linoleic Acid Ameliorates 2, 4-dinitrofluorobenzene-Induced Atopic Dermatitis-like Lesions in BALB/c Mice
Crocin 📋✍⛔30400140Crocin Ameliorates Atopic Dermatitis Symptoms by Down Regulation of Th2 Response via Blocking of NF-κB/STAT6 Signaling Pathways in Mice
Cumin 📋 ⛔37430973Aqueous Extract from Cuminum cyminum L. Seed Alleviates Ovalbumin-Induced Allergic Rhinitis in Mouse via Balancing of Helper T Cells
Diosmetin 📋 33045572Anti-inflammatory effects of natural flavonoid diosmetin in IL-4 and LPS-induced macrophage activation and atopic dermatitis model
Diosmin 📋✍⛔33302042Diosmin restores the skin barrier by targeting the aryl hydrocarbon receptor in atopic dermatitis
Eclipta Alba 📋✍ 37487966A methanolic extract of Eclipta prostrata (L.) L. decreases inflammation in a murine model of chronic allergic asthma via inhibition of the NF-kappa-B pathway
Eicosapentaenoic Acid 📋✍⛔36777980Evaluating the Effect of Eicosapentaenoic Acid in Children With Atopic Dermatitis: A Randomized Triple-Blind Clinical Trial
Elderberry 📋✍⛔33571040A Comparison of the Effect of Topical Preparation of Sambucus ebulus L. and Hydrocortisone on Hand Eczema: A Double-Blind Randomized Controlled Trial
Essential Fatty Acids 📋✍ 18477332Efficacy of an essential fatty acid-enriched diet in managing canine atopic dermatitis: a randomized, single-blinded, cross-over study
Food 📋 34876306Atopic dermatitis and nutrition
Formononetin 📋 33013383Formononetin Attenuates Airway Inflammation and Oxidative Stress in Murine Allergic Asthma
Gamma-Linolenic Acid 📋✍⛔15500483Alterations of mast cell mediator production and release by gamma-linolenic and docosahexaenoic acid
Gingerol 📋✍ 34934427Ginger-derived compounds exert in vivo and in vitro anti-asthmatic effects by inhibiting the T-helper 2 cell-mediated allergic response
Glabridin 📋 37584465Immunomodulatory effect of glabridin in ovalbumin induced allergic asthma and its comparison with methylprednisolone in a preclinical rodent model
Gotu Kola 📋✍⛔32033291Inhibitory Effect of Centella asiatica Extract on DNCB-Induced Atopic Dermatitis in HaCaT Cells and BALB/c Mice
Green Tea Polyphenols 📋✍⛔35739968Skin Care Product Rich in Antioxidants and Anti-Inflammatory Natural Compounds Reduces Itching and Inflammation in the Skin of Atopic Dermatitis Patients
Honey 📋✍⛔35909403Anti-inflammatory properties of raw honey and its clinical applications in daily practice
Honeysuckle 📋 ⛔36889421A homogeneous Lonicera japonica polysaccharide alleviates atopic dermatitis by promoting Nrf2 activation and NLRP3 inflammasome degradation via p62
Iodine 📋✍⛔38078671Nasal instillation of povidone-iodine ameliorates ongoing mucosal inflammation in a pre-sensitized murine model of Der p1-induced allergic rhinitis
Magnesium 📋✍⛔16406247Dietary intake of seaweed and minerals and prevalence of allergic rhinitis in Japanese pregnant females: baseline data from the Osaka Maternal and Child Health Study
Maitake Mushrooms 📋 ⛔38053833Extracts of Grifola frondosa inhibit the MAPK signaling pathways involved in keratinocyte inflammation and ameliorate atopic dermatitis
Myricetin 📋 ⛔36575998Myricetin treatment has ameliorative effects in DNFB-induced atopic dermatitis mice under high-fat conditions
N-Acetyl Cysteine 📋✍⛔38376812N-Acetyl Cysteine Augments Adipose Tissue-Derived Stem Cell Efficacy on Inflammatory Markers and Regulatory T Cell System Balance in an Allergic Asthma Model
NMN 📋✍⛔38064810Nicotinamide mononucleotide attenuates airway epithelial barrier dysfunction via inhibiting SIRT3 SUMOylation in asthma
Ollive Leaf extract 📋✍⛔33571899A combination of Olea europaea leaf extract and Spirodela polyrhiza extract alleviates atopic dermatitis by modulating immune balance and skin barrier function in a 1-chloro-2,4-dinitrobenzene-induced murine model
Peppermint Essential Oil 📋✍⛔36578435Protective effects of inhalation of essential oils from Mentha piperita leaf on tight junctions and inflammation in allergic rhinitis
Perilla 📋✍ 36322828Antiasthmatic Compounds Targeting β2-Adrenergic Receptor from Perilla frutescens Improved Lung Inflammation by Inhibiting the NF-κB Signaling Pathway
Persimmon 📋 ⛔33401337Persimmon leaf extract protects mice from atopic dermatitis by inhibiting T cell activation via regulation of the JNK pathway
Puerarin 📋✍⛔29524423The Suppressive Effect of Puerarin on Atopic Dermatitis-Like Skin Lesions Through Regulation of Inflammatory Mediators in Vitro and in Vivo
Rosemary 📋✍⛔37918369Inhalation of Spray-Dried Extract of Salvia rosmarinus Spenn Alleviates Lung Inflammatory, Oxidative, and Remodeling Changes in Asthmatic Rats
Tangeretin 📋 31030096Tangeretin promotes regulatory T cell differentiation by inhibiting Notch1/Jagged1 signaling in allergic rhinitis
Tetrahydrocurcumin 📋✍ 34116562Tetrahydrocurcumin alleviates allergic airway inflammation in asthmatic mice by modulating the gut microbiota
TUDCA 📋✍⛔31045581Conjugated bile acids attenuate allergen-induced airway inflammation and hyperresponsiveness by inhibiting UPR transducers
Urolithins 📋 36961550Network pharmacology and molecular docking to explore the potential mechanism of urolithin A in combined allergic rhinitis and asthma syndrome
Vitamin A 📋✍⛔34920650Studying the Effects of Vitamin A on the Severity of Allergic Rhinitis and Asthma
Vitamin K2 📋✍⛔33390552Vitamin K2 Suppresses Proliferation and Inflammatory Cytokine Production in Mitogen-Activated Lymphocytes of Atopic Dermatitis Patients through the Inhibition of Mitogen-Activated Protein Kinases
Vitexin 📋 35026520Vitexin restores lung homeostasis by targeting vicious loop between inflammatory aggravation and autophagy mediated via multiple redox cascade and myeloid cells alteration in experimental allergic asthma
Wogonin 📋✍⛔29977652Anti-inflammatory Effect of Wogonin on Allergic Responses in Ovalbumin-Induced Allergic Rhinitis in the Mouse
5-HTP 📋✍⛔22842218Inhibition of allergic inflammation by supplementation with 5-hydroxytryptophan
Aloin 📋 37781715Exploration of the mechanism of aloin ameliorates of combined allergic rhinitis and asthma syndrome based on network pharmacology and experimental validation
Amygdalin 📋✍⛔38085145Amygdalin Improves Allergic Asthma via the Thymic Stromal Lymphopoietin-dendritic Cell-OX40 Ligand Axis in a Mouse Model
Andrographolide 📋 26929603Andrographolide suppresses thymic stromal lymphopoietin in phorbol myristate acetate/calcium ionophore A23187-activated mast cells and 2,4-dinitrofluorobenzene-induced atopic dermatitis-like mice model
Anethole 📋 29062168Illicium verum Extract and Trans-Anethole Attenuate Ovalbumin-Induced Airway Inflammation via Enhancement of Foxp3 + Regulatory T Cells and Inhibition of Th2 Cytokines in Mice
Anise 📋✍⛔34493326The extract of black cumin, licorice, anise, and black tea alleviates OVA-induced allergic rhinitis in mouse via balancing activity of helper T cells in lung
Anthocyanins 📋✍⛔32842205[To explore the therapeutic effect of myrtle oil, anthocyanin and hyaluronic acid in combination with topical application on allergic rhinitis in rats exposed to PM2.5]
Antioxidants 📋 ⛔35502578Efficacy and safety profile of antioxidants in the treatment of atopic dermatitis: A systematic review and meta-analysis of randomized controlled trials
Apple 📋 ⛔33747463Boysenberry and apple juice concentrate reduced acute lung inflammation and increased M2 macrophage-associated cytokines in an acute mouse model of allergic airways disease
Apple Polyphenols 📋 ⛔35739968Skin Care Product Rich in Antioxidants and Anti-Inflammatory Natural Compounds Reduces Itching and Inflammation in the Skin of Atopic Dermatitis Patients
Arctigenin 📋 32714398A Natural Compound Mixture Containing Arctigenin, Hederagenin, and Baicalein Alleviates Atopic Dermatitis in Mice by Regulating HPA Axis and Immune Activity
Ashwagandha 📋✍⛔37405114Modulation of Immunological, Biochemical, and Histopathological Changes of Airway Remodeling by Withania somnifera in an Experimental Model of Allergic Asthma in Rats
Aspirin 📋 ⛔37691954Potential causal association between aspirin use and the reduced risk of hayfever or allergic rhinitis: a Mendelian randomization study
Bee Venom 📋✍⛔31786805Anti-inflammatory effect of bee venom in phthalic anhydride-induced atopic dermatitis animal model
Beta-Carotene 📋✍⛔26992660Oral administration of β-carotene or lycopene prevents atopic dermatitis-like dermatitis in HR-1 mice
Beta-Glucan 📋✍⛔38603862β-glucan mitigates ovalbumin-induced airway inflammation by preventing oxidative stress and CD8+ T cell infiltration
Beta-Sitosterol 📋✍⛔36481301β-sitosterol targets glucocorticoid receptor to reduce airway inflammation and remodeling in allergic asthma
Bitter Melon 📋✍⛔35257554Momordica charantia L. improves airway hyperresponsiveness and suppresses inflammation in a murine model of allergic asthma
Black Tea 📋✍⛔34493326The extract of black cumin, licorice, anise, and black tea alleviates OVA-induced allergic rhinitis in mouse via balancing activity of helper T cells in lung
Bromelain 📋✍⛔22894886Bromelain limits airway inflammation in an ovalbumin-induced murine model of established asthma
Burdock 📋 ⛔21303540Anti-allergic and anti-inflammatory effects of butanol extract from Arctium Lappa L
Calcium 📋✍⛔16406247Dietary intake of seaweed and minerals and prevalence of allergic rhinitis in Japanese pregnant females: baseline data from the Osaka Maternal and Child Health Study
Camellia 📋 ⛔37765323Camellia sinensis (L.) Kuntze Extract Attenuates Ovalbumin-Induced Allergic Asthma by Regulating Airway Inflammation and Mucus Hypersecretion
Camphor 📋✍⛔31341557Cinnamomum camphora Leaves Alleviate Allergic Skin Inflammatory Responses In Vitro and In Vivo
Carnosol 📋 32632049Suppressive Effect of Carnosol on Ovalbumin-Induced Allergic Asthma
Cat's Claw 📋✍⛔29432856Aqueous extracts from Uncaria tomentosa (Willd. ex Schult.) DC. reduce bronchial hyperresponsiveness and inflammation in a murine model of asthma
Catechins 📋 35743851Ameliorative Effect of a Neoteric Regimen of Catechin plus Cetirizine on Ovalbumin-Induced Allergic Rhinitis in Rats
Celery 📋 ⛔32202321Anti-atopic Dermatitis Effects of Hydrolyzed Celery Extract in Mice
Chamomile Essential Oil 📋✍⛔31782320Evaluation of chamomile oil and nanoemulgels as a promising treatment option for atopic dermatitis induced in rats
Chlorella 📋✍⛔26404252Chlorella vulgaris Attenuates Dermatophagoides Farinae-Induced Atopic Dermatitis-Like Symptoms in NC/Nga Mice
Chokeberry 📋✍⛔36670888Extract of Wheatgrass and Aronia Mixture Ameliorates Atopic Dermatitis-Related Symptoms by Suppressing Inflammatory Response and Oxidative Stress In Vitro and In Vivo
Chrysanthemum 📋✍⛔22454686Topical Application of Chrysanthemum indicum L. Attenuates the Development of Atopic Dermatitis-Like Skin Lesions by Suppressing Serum IgE Levels, IFN-γ, and IL-4 in Nc/Nga Mice
Coumaric acid 📋 33437169p-coumaric acid, an active ingredient of Panax ginseng, ameliolates atopic dermatitis-like skin lesions through inhibition of thymic stromal lymphopoietin in mice
Cryptotanshinone 📋 29845271Cryptotanshinone inhibits IgE‑mediated degranulation through inhibition of spleen tyrosine kinase and tyrosine‑protein kinase phosphorylation in mast cells
D-Mannose 📋✍⛔36327873D-Mannose ameliorates DNCB-induced atopic dermatitis in mice and TNF-α-induced inflammation in human keratinocytes via mTOR/NF-κB pathway
DIM 📋✍⛔333093063,3'-Diindolylmethane alleviates acute atopic dermatitis by regulating T cell differentiation in a mouse model
Echinacea 📋✍⛔28610718Echinacea Purpurea-Derived Alkylamides Exhibit Potent Anti-Inflammatory Effects and Alleviate Clinical Symptoms of Atopic Eczema
Egg 📋 ⛔34648974Inverse associations between food diversity in the 2 nd year of life and allergic diseases
Essential Oils 📋 ⛔38625386The use of essential oils in atopic dermatitis: a review
Eugenol 📋 31848500[Effect of methyl eugenol on nasal mucosal aquaporin 5 in rats with allergic rhinitis]
Fenugreek 📋✍⛔27939889Trigonella Foenum-Graecum Alleviates Airway Inflammation of Allergic Asthma in Ovalbumin-Induced Mouse Model
Fiber 📋✍⛔35990418Dietary fibre in relation to asthma, allergic rhinitis and sensitization from childhood up to adulthood
Fisetin 📋✍⛔22290391Fisetin, a bioactive flavonol, attenuates allergic airway inflammation through negative regulation of NF-κB
Fish 📋 ⛔17634174Fish and fat intake and prevalence of allergic rhinitis in Japanese females: the Osaka Maternal and Child Health Study
Fish Collagen 📋✍⛔37689763Anti-atopic dermatitis effect of fish collagen on house dust mite-induced mice and HaCaT keratinocytes
Fo-Ti Root 📋✍⛔26916919Polygonum multiflorum Decreases Airway Allergic Symptoms in a Murine Model of Asthma
Fucoxanthin 📋✍⛔32235696Fucoxanthin Ameliorates Atopic Dermatitis Symptoms by Regulating Keratinocytes and Regulatory Innate Lymphoid Cells
Galangal 📋✍⛔34656059Alpinia officinarum water extract inhibits the atopic dermatitis-like responses in NC/Nga mice by regulation of inflammatory chemokine production
Geniposide 📋 34847477Gardenia jasminoides extract ameliorates DfE-induced atopic dermatitis in mice through restoration of barrier function and T-helper 2-mediated immune response
Geranium Essential Oil 📋 ⛔27034695Effect of Inhalation of Aromatherapy Oil on Patients with Perennial Allergic Rhinitis: A Randomized Controlled Trial
Ginger extract 📋✍⛔26403321Prevention of allergic rhinitis by ginger and the molecular basis of immunosuppression by 6-gingerol through T cell inactivation
Ginkgetin 📋 16651744Effects of anti-inflammatory biflavonoid, ginkgetin, on chronic skin inflammation
Ginkgolides 📋 22849842In vitro suppression of lymphocyte activation in patients with seasonal allergic rhinitis and pollen-related asthma by cetirizine or azelastine in combination with ginkgolide B or astaxanthin
Glycyrrhetinic Acid 📋 3521044918β-Glycyrrhetinic acid suppresses allergic airway inflammation through NF-κB and Nrf2/HO-1 signaling pathways in asthma mice
Goji Berry 📋✍⛔37780223Protective effect of Lycium barbarum leaf extracts on atopic dermatitis: in vitro and in vivo studies
Grape 📋 ⛔36741360Protective effects of dietary grape against atopic dermatitis-like skin lesions in NC/NgaTndCrlj mice
Grape Seed extract 📋✍⛔22836658Grape seed proanthocyanidin extract attenuates allergic inflammation in murine models of asthma
Grapefruit 📋 ⛔33752061Protective effects of total flavonoids from Qu Zhi Qiao (fruit of Citrus paradisi cv. Changshanhuyou) on OVA-induced allergic airway inflammation and remodeling through MAPKs and Smad2/3 signaling pathway
Haritaki 📋✍⛔35830757Terminalia chebula Retz. extract ameliorates the symptoms of atopic dermatitis by regulating anti-inflammatory factors in vivo and suppressing STAT1/3 and NF-ĸB signaling in vitro
Hesperetin 📋 22454667Hesperetin, a Selective Phosphodiesterase 4 Inhibitor, Effectively Suppresses Ovalbumin-Induced Airway Hyperresponsiveness without Influencing Xylazine/Ketamine-Induced Anesthesia
Hesperidin 📋✍⛔30488351The amendatory effect of hesperidin and thymol in allergic rhinitis: an ovalbumin-induced rat model
Honokiol 📋 35074454Honokiol suppresses 2,6-dinitrochlorobenzene-induced atopic dermatitis in mice
Hydroxytyrosol 📋 31645146Chemical composition, antioxidant activities, in an allergic asthma model, of Olea europaea L. leaf extracts from Collo (Skikda, Algeria)
Icariin 📋✍ 37602424Icariin restrains NLRP3 inflammasome-mediated Th2 immune responses and ameliorates atopic dermatitis through modulating a novel lncRNA MALAT1/miR-124-3p axis
Indian Mulberry 📋✍⛔36639978Morinda officinalis extract exhibits protective effects against atopic dermatitis by regulating the MALAT1/miR-590-5p/CCR7 axis
Iron 📋✍⛔35769558Iron-Deficiency in Atopic Diseases: Innate Immune Priming by Allergens and Siderophores
Isoliquiritigenin 📋 29026975Effect of isoliquiritigenin for the treatment of atopic dermatitis-like skin lesions in mice
Kale 📋 35739968Skin Care Product Rich in Antioxidants and Anti-Inflammatory Natural Compounds Reduces Itching and Inflammation in the Skin of Atopic Dermatitis Patients
Kimchi 📋 ⛔34737993Effect of Lactic Acid Strains Isolated from Kimchi on Atopic Dermatitis and Immunomodulation in NC/Nga Mice
Kudzu Root 📋✍⛔35658632Isoorientin ameliorates OVA-induced asthma in a murine model of asthma
L-Histidine 📋✍⛔33000160l-Histidine Supplementation in Adults and Young Children with Atopic Dermatitis (Eczema)
L-Tryptophan 📋✍⛔38318507Tryptophan, an important link in regulating the complex network of skin immunology response in atopic dermatitis
Lavender Essential Oil 📋✍⛔38181031Aromatic oil from lavender as an atopic dermatitis suppressant
Lemongrass 📋✍⛔26048391The anti-allergic activity of Cymbopogon citratus is mediated via inhibition of nuclear factor kappa B (Nf-Κb) activation
Licochalcones 📋 24028304Attenuation of allergic airway inflammation in a murine model of asthma by Licochalcone A
Linoleic Acid 📋✍⛔33865303A cream containing linoleic acid, 5% dexpanthenol and ceramide in the treatment of atopic dermatitis
Lipoic Acid 📋✍⛔32719431Anti-allergic rhinitis activity of α-lipoic acid via balancing Th17/Treg expression and enhancing Nrf2/HO-1 pathway signaling
Loquat 📋✍⛔31310829Eriobotrya japonica leaf extract attenuates airway inflammation in ovalbumin-induced mice model of asthma
Lupeol 📋 37098554Lupeol alleviates atopic dermatitis-like skin inflammation in 2,4-dinitrochlorobenzene/Dermatophagoides farinae extract-induced mice
Magnolia 📋✍⛔37955529Effects of Magnoliae Flos on Atopic Dermatitis-Like Inflammation Evaluated via Extracellular Signal-regulated Kinase or Signal Transducers and Activators of Transcription 1/3 Signalling Pathways
Malva Sylvestris 📋 ⛔33100212Efficacy of Short Term Topical Malva Sylvestris L. Cream in Pediatric Patients with Atopic Dermatitis: A Randomized Double-Blind Placebo-Controlled Clinical Trial
Marigold 📋✍⛔34425472Effects of topical application of a tri-herb formula on inflammatory dry-skin condition in mice with oxazolone-induced atopic dermatitis
Mastic 📋✍⛔34332283Topical treatment with mastic (resin from Pistacia lentiscus) elicits anti-inflammatory and anti-pruritic responses by modulating keratinocyte activation in a mouse model of allergic dermatitis
Milk 📋 ⛔34978666Association of milk intake with hay fever, asthma, and lung function: a Mendelian randomization analysis
Moringa Oleifera 📋✍⛔29576799Advanced Effect of Moringa oleifera Bioconversion by Rhizopus oligosporus on the Treatment of Atopic Dermatitis: Preliminary Study
Motherwort 📋✍⛔34421593Trigonelline, An Alkaloid From Leonurus japonicus Houtt., Suppresses Mast Cell Activation and OVA-Induced Allergic Asthma
MSM 📋✍⛔30497995Evaluating the Impacts of Methylsulfonylmethane on Allergic Rhinitis After a Standard Allergen Challenge: Randomized Double-Blind Exploratory Study
Mulberry 📋 ⛔36610150Morus alba fruits attenuates atopic dermatitis symptoms and pathology in vivo and in vitro via the regulation of barrier function, immune response and pruritus
Myrtle 📋✍⛔32641957Anti-Inflammatory and Anti-Oxidative Effects of Myrtenol in the Rats with Allergic Asthma
Myrtle Essential Oil 📋✍⛔32842205[To explore the therapeutic effect of myrtle oil, anthocyanin and hyaluronic acid in combination with topical application on allergic rhinitis in rats exposed to PM2.5]
Naringin 📋✍⛔32698069Cellulose microsponges based gel of naringenin for atopic dermatitis: Design, optimization, in vitro and in vivo investigation
Neferine 📋 34361003Effect of Neferine on DNCB-Induced Atopic Dermatitis in HaCaT Cells and BALB/c Mice
Oleanolic Acid 📋 37021507Oleanolic Acid Acetate Inhibits Mast Cell Activation in Ovalbumin-Induced Allergic Airway Inflammation
Oleuropein 📋 35964244Oleuropein attenuates inflammation and regulates immune responses in a 2,4-dinitrochlorobenzene-induced atopic dermatitis mouse model
Olive Oil 📋✍⛔33072415Comparing the Therapeutic Effects of Aloe vera and Olive Oil Combination Cream versus Topical Betamethasone for Atopic Dermatitis: A Randomized Double-blind Clinical Trial
Onion 📋✍⛔38584568Treatment with onion bulb extract both prevents and reverses allergic inflammation in a murine model of asthma
Paeoniflorin 📋 30076630Paeoniflorin inhibits mast cell-mediated allergic inflammation in allergic rhinitis
Papaya 📋✍⛔28732802Carica papaya ameliorates allergic asthma via down regulation of IL-4, IL-5, eotaxin, TNF-α, NF-ĸB, and iNOS levels
Pau d'Arco 📋✍⛔29736153Tabetri™ ( Tabebuia avellanedae Ethanol Extract) Ameliorates Atopic Dermatitis Symptoms in Mice
PEA 📋✍⛔38408443Efficacy of topical palmitoylethanolamide (Levagen+) for the management of eczema symptoms: A double blind, comparator controlled, randomized clinical trial
Pectin 📋✍⛔38417857Oral Administration of Apple Pectin Solution Improves Atopic Dermatitis in a Mouse Model
Peppermint 📋✍⛔11201253Effects of peppermint (Mentha piperita L.) extracts on experimental allergic rhinitis in rats
Piperine 📋✍⛔32392825Piperine Ameliorates Trimellitic Anhydride-Induced Atopic Dermatitis-Like Symptoms by Suppressing Th2-Mediated Immune Responses via Inhibition of STAT6 Phosphorylation
Polydatin 📋✍ 36906289Polydatin inhibits mitochondrial damage and mitochondrial ROS by promoting PINK1-Parkin-mediated mitophagy in allergic rhinitis
Polyphenols 📋 37830192Recent Advancement and Novel Application of Natural Polyphenols for the Treatment of Allergy Asthma: From Phytochemistry to Biological Implications
Polypodium Leucotomos 📋✍⛔22560125Polypodium leucotomos extract in atopic dermatitis: a randomized, double-blind, placebo-controlled, multicenter trial
Pomegranate 📋 ⛔36330147Pomegranate extract supplementation improves lung function parameters and IL-35 expression in participants with mild and moderate persistent allergic asthma: A randomized, double-blind, placebo-controlled trial
Pomegranate Seed extract 📋 ⛔36762119Does pomegranate extract supplementation improve the clinical symptoms of patients with allergic asthma? A double-blind, randomized, placebo-controlled trial
Poria Mushrooms 📋✍ 33919400Poria cocos Modulates Th1/Th2 Response and Attenuates Airway Inflammation in an Ovalbumin-Sensitized Mouse Allergic Asthma Model
PQQ 📋✍⛔36345503Pyrroloquinoline Quinone Administration Alleviates Allergic Airway Inflammation in Mice by Regulating the JAK-STAT Signaling Pathway
Pterostilbene 📋✍⛔37069463Pterostilbene reduces the progression of atopic dermatitis via modulating inflammatory and oxidative stress biomarkers in mice
Punicalagin 📋✍⛔36651367Punicalagin attenuated allergic airway inflammation via regulating IL4/IL-4Rα/STAT6 and Notch- GATA3 pathways
Radish 📋 ⛔38543055Anti-Atopic Effect of Scutellaria baicalensis and Raphanus sativus on Atopic Dermatitis-like Lesions in Mice by Experimental Verification and Compound-Target Prediction
Raspberry 📋✍⛔35179167Alleviation effects of Rubus coreanus Miquel root extract on skin symptoms and inflammation in chronic atopic dermatitis
Red Sage 📋✍⛔30599896Protective effects and active ingredients of Salvia miltiorrhiza Bunge extracts on airway responsiveness, inflammation and remodeling in mice with ovalbumin-induced allergic asthma
Rehmannia 📋✍⛔35168697Anti-atopic dermatitis effects of Parasenecio auriculatus via simultaneous inhibition of multiple inflammatory pathways
Saffron 📋✍⛔32628613Neural Network-Based Clinical Prediction System for Identifying the Clinical Effects of Saffron (Crocus Sativus L) Supplement Therapy on Allergic Asthma: Model Evaluation Study
Salidroside 📋 32070919Salidroside suppresses group 2 innate lymphoid cell-mediated allergic airway inflammation by targeting IL-33/ST2 axis
Salvianolic Acid 📋 34691223Salvianolic Acid A Suppresses DNCB-Induced Atopic Dermatitis-Like Symptoms in BALB/c Mice
Schisandrins 📋 35085518Schisandrin B promotes Foxp3 + regulatory T cell expansion by activating heme oxygenase-1 in dendritic cells and exhibits immunomodulatory effects in Th2-mediated allergic asthma
Scutellarein 📋 35771623Scutellarein Attenuates Atopic Dermatitis by Selectively Inhibiting Transient Receptor Potential Vanilloid 3
Selenium 📋✍⛔33422684Effects of Vitamin E and Selenium on Allergic Rhinitis and Asthma Pathophysiology
Shiitake Mushrooms 📋✍⛔27483228Chemical Composition and Inhibitory Effect of Lentinula edodes Ethanolic Extract on Experimentally Induced Atopic Dermatitis in Vitro and in Vivo
Shogaol 📋 34934427Ginger-derived compounds exert in vivo and in vitro anti-asthmatic effects by inhibiting the T-helper 2 cell-mediated allergic response
St. Johns Wort Oil 📋 ⛔12807340Topical Treatment of Atopic Dermatitis With St. John's Wort Cream--A Randomized, Placebo Controlled, Double Blind Half-Side Comparison
Star Anise 📋✍⛔29062168Illicium verum Extract and Trans-Anethole Attenuate Ovalbumin-Induced Airway Inflammation via Enhancement of Foxp3 + Regulatory T Cells and Inhibition of Th2 Cytokines in Mice
Stigmasterol 📋 36788676Stigmasterol alleviates allergic airway inflammation and airway hyperresponsiveness in asthma mice through inhibiting substance-P receptor
Stinging Nettle 📋✍⛔38675586Evaluation of Urtica dioica Phytochemicals against Therapeutic Targets of Allergic Rhinitis Using Computational Studies
Sunflower 📋 ⛔36108372Oral administration of Helianthus annuus leaf extract ameliorates atopic dermatitis by modulation of T cell activity in vivo
Sunflower Oil 📋✍⛔38247218Ozonated Sunflower Oil (OSO) alleviates inflammatory responses in oxazolone-induced atopic dermatitis (AD)-like mice and LPS- treated RAW 264.7 cells
Tannic Acid 📋✍⛔34126339Anti-asthmatic effects of tannic acid from Chinese natural gall nuts in a mouse model of allergic asthma
Tanshinone 📋 35167426Tanshinone IIA alleviates ovalbumin-induced allergic rhinitis symptoms by inhibiting Th2 cytokine production and mast cell histamine release in mice
Thymol 📋✍⛔30488351The amendatory effect of hesperidin and thymol in allergic rhinitis: an ovalbumin-induced rat model
Tribulus Terrestris 📋✍⛔29348776Effects of the Fruit Extract of Tribulus terrestris on Skin Inflammation in Mice with Oxazolone-Induced Atopic Dermatitis through Regulation of Calcium Channels, Orai-1 and TRPV3, and Mast Cell Activation
Turmeric 📋✍⛔32582180Crude Turmeric Extract Improves the Suppressive Effects of Lactobacillus rhamnosus GG on Allergic Inflammation in a Murine Model of House Dust Mite-Induced Asthma
UDCA 📋✍⛔38490296Ursodeoxycholic acid alleviates atopic dermatitis-associated inflammatory responses in HaCaT and RBL-2H3 cells and DNCB/DFE-treated mice
Ursolic Acid 📋✍⛔36996741Ursolic acid ameliorates DNCB-induced atopic dermatitis-like symptoms in mice by regulating TLR4/NF-κB and Nrf2/HO-1 signaling pathways
Vitamin C 📋✍⛔30118241Effects of aerobic exercise and vitamin C supplementation on rhinitis symptoms in allergic rhinitis patients
Walnut 📋 ⛔35401757Amelioration of Ovalbumin-Induced Allergic Asthma by Juglans regia via Downregulation of Inflammatory Cytokines and Upregulation of Aquaporin-1 and Aquaporin-5 in Mice
White Fungus 📋 36091780Tremella fuciformis polysaccharides alleviate induced atopic dermatitis in mice by regulating immune response and gut microbiota
Witch Hazel 📋✍⛔36012541Unveiling the Ability of Witch Hazel ( Hamamelis virginiana L.) Bark Extract to Impair Keratinocyte Inflammatory Cascade Typical of Atopic Eczema
Zeaxanthin 📋✍⛔36086967Zeaxanthin attenuates OVA-induced allergic asthma in mice by regulating the p38 MAPK/β-catenin signaling pathway